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Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis

Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01240174
Enrollment
400
Registered
2010-11-15
Start date
2011-03-31
Completion date
2014-07-31
Last updated
2017-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchitis, Cough

Keywords

Antibiotic, Antimicrobial, Prescribing, Cough, Acute Bronchitis

Brief summary

Studies show, guidelines state, and performance measures assert that antibiotic prescribing for uncomplicated acute bronchitis is inappropriate. However, clinicians prescribe antimicrobials in over 60% of the 22.5 million acute bronchitis visits in the United States each year. Previous successful interventions have only reduced the antimicrobial prescribing rate to 40% or 50%. It is unknown if the antimicrobial prescribing rate for acute bronchitis can be brought to near zero percent in actual practice while maintaining patient safety and satisfaction. The goal of this study is to develop an Electronic Health Record (EHR)-integrated algorithm for the diagnosis and treatment of adults with acute bronchitis with a goal of reducing the antibiotic prescribing rate to near zero percent.

Detailed description

We will use a multi-modal implementation - including computerized decision support, reporting tools, and clinician feedback - and quality improvement techniques to ensure adherence to the algorithm and reduce the antimicrobial prescribing rate to near zero percent. The duration of the intervention will be 4 years.

Interventions

BEHAVIORALDemonstration of near zero antibiotic prescribing for patients with acute bronchitis

A controlled, continuously-monitored, implementation of an EHR-integrated diagnosis and treatment algorithm for acute bronchitis in a large, diverse primary care practice.

Sponsors

Agency for Healthcare Research and Quality (AHRQ)
CollaboratorFED
Brigham and Women's Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
Yes

Inclusion criteria

* first visit in 30 days, age 18-64, has a cough of less than 3 weeks duration

Exclusion criteria

* infiltrate on chest x-ray, has chronic lung disease

Design outcomes

Primary

MeasureTime frameDescription
Antibiotic prescribing rate30 daysThe antibiotic prescribing rate for patients with acute bronchitis

Secondary

MeasureTime frame
Patient symptoms21 days
Patient satisfaction21 days
Patient safety30 days
Healthcare costs30 days
The capture and description of the components that had the greatest effect on the antimicrobial prescribing rate3 years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026