Smoking, Stress
Conditions
Brief summary
This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence. This analysis will help to identify factors that might be important for smoking behavior and nicotine addiction. The results from this study will contribute to improve campaigns for smoking prevention and treatments for smoking cessation.
Interventions
None listed
Sponsors
Oregon Health and Science University
Study design
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
25 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy adults * age 25-55
Exclusion criteria
* alcohol or drug addiction * unstable significant medical problems * neurologic disease * medications known to affect CNS function or impact physiologic parameters measured in the study * significant visual impairment * breath carbon monoxide (BCO) level of less than 10 ppm for smokers * breath carbon monoxide (BCO) level of more than 5 ppm for non-smokers * for heavy regular smokers: erratic smoking history (i.e. they must have smoked an average of 15 cigarettes daily for at least one year)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Electroencephalography | Changes from baseline during a hard cognitive task | Electroencephalography will be measured during performance on a hard cognitive task. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Salivary cortisol | Changes from baseline during performance on a hard cognitive task | Salivary cortisol will be measured at baseline, during a hard cognitive task and 30 minutes after the cognitive task. |
Countries
United States
Outcome results
None listed