Dental Plaque, Denture Stomatitis, Oral Candidiasis, Oral Hygiene
Conditions
Keywords
Chloramine T, Complete Denture, Dental Plaque Index, Dentifrice, Denture Bases, Denture Cleansers, Edentulous Mouth, Fluorosurfactant, Oral Health, Toothpaste
Brief summary
This trial aims to evaluate the efficacy of three experimental dentifrices to remove denture biofilm. Complete denture wearers will be instructed to brush their dentures with a specific toothbrush and four compositions: (1) A proprietary denture-specific paste (active comparator); (2) 0.2% chloramine T; (3) 1.0% chloramine T; (4) 0.01% fluorosurfactant. Each treatment will be used for periods of 7 days, and participants will be randomized to use them according to one of four sequences.
Interventions
OTHERDentifrice
Dentifrices (4 formulations) used as auxiliary agents for brushing complete dentures.
Sponsors
Raphael Freitas de Souza
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
45 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Completely edentulous * Good general health * Patients requesting new complete dentures (volunteers will receive the interventions before new complete dentures) * Regular wearing of the same maxillary and mandibular complete dentures for 3 to 10 years * Both denture bases and artificial teeth should be composed by acrylic resin
Exclusion criteria
* Unsatisfactory complete dentures in use (i.e. with poor fitting, relining or fractures) * Absence of deposits of biofilm at baseline
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Denture plaque coverage area (%) | 7 days | Relation between stained area and total surface area on the internal surface of maxillary complete dentures. |
Countries
Brazil
Outcome results
None listed