The Impact of Food on Blood Sugar in People With Type 2 Diabetes

Evaluation of the Glycemic Impact of Food in Patients With Type 2 Diabetes Taking Glargine and/or Exenatide

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01237314

Acronym

REACT2

Enrollment

Registered

2010-11-09

Start date

2010-11-30

Completion date

2013-05-31

Last updated

2015-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

type 2 diabetes, metformin, glargine, exenatide, glycemic impact of food, continuous glucose monitoring

Brief summary

This study will record the impact of food on blood glucose levels using continuous glucose monitoring (CGM). The investigators think the impact will improve as medication doses are adjusted. The investigators also think that the impact will differ depending on the type of medication taken.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Study participants who are consented for the primary study and have not yet done the baseline CGM data collection at week -2-0.

Exclusion criteria

* Study participants who are unable to complete the baseline CGM data collection at week -2-0. * Study participants who are allergic to or have a food intolerance to any of the foods in the fixed meal

Design outcomes

Primary

Measure	Time frame	Description
4-hour glycemic response at 3 time points	4 hours	The four-hour glycemic response includes: four-hour post-meal area under the median interstitial glucose curve, post-meal interstitial glucose peak, time to peak, time to return to pre-prandial level (to within 10% of baseline with a maximum of the 4-hour post-meal fast), difference between peak and baseline, average rate of change in interstitial glucose across the 4 hour post-meal period, and percent of the 4-hour post-meal glucose readings \>180 mg/dL.

Countries

United States

Outcome results