Carcinoma, Hepatocellular
Conditions
Brief summary
The current treatment guidelines of hepatocellular carcinoma (HCC) of the American and European Associations for the Study of Liver Disease are based on the Barcelona-Clinic-Liver-Cancer classification (BCLC), which does not recommend surgery in patients with large, multinodular and macrovascular invasive disease. The aim of this study was to investigate the role of hepatic resection in a large retrospective multicentric cohort of patients resected for HCC regardless of the BCLC indications.
Interventions
None listed
Sponsors
University of Milan
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* clinical diagnosis of hepatocellular carcinoma * candidate to liver resection as a curative treatment
Exclusion criteria
* uncertain diagnosis of hepatocellular carcinoma * uncertain follow-up data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival of resected patients for HCC | — | The primary endpoint of the study was the overall survival of patients resected for HCC in any stage of the BCLC classification. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Disease-free survival of resected patients for HCC | — | The secondary endpoint was the disease-free survival of patients resected for HCC among the BCLC stages. |
Outcome results
None listed