Gingivitis, Dental Plaque Accumulation
Conditions
Keywords
Clinical Trial, Prevention Mouthrinse
Brief summary
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque. Essential oils and delmopinol mouthrinses are effective to reduce dental plaque accumulation and gingivitis. Also an effect on dental bacteria can be found. The study hypothesis states that there are no differences between the mouthrinses on the reduction of gingivitis and dental plaque accumulation as well on the bacterial counts of Streptococcus mutans, Lactobacillus, aerobic and anaerobic bacteria.
Interventions
Commercial mouthrinse with manufacturer's use indication
DRUGDelmopinol mouthrinse
Commercial mouthrinse with manufacturer's use indication
Sponsors
Instituto Piaget
University of Lisbon
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patient at the dental hygiene clinic of Faculdade de Medicina Dentária * Signature of consent form * Have, at least, two quadrant with 6 teeth each * Gingival Index at baseline less than 3 * Presence of dental plaque
Exclusion criteria
* Use of a mouthrinse * Dental Hygiene appointment in the past 6 months * Use of antibiotics in teh past 3 months * Presence of extensive caries and fractures of teeth
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Loe & Silness Gingival Index (1963) | change from baseline in gingival index at two weeks | data collected at the begining of the study and two weeks after mouthrinse usage. |
| Quigley, Hein & Turesky Dental Plaque Index (1970) | change from baseline in plaque index at two weeks | data collected at the begining of the study and two weeks after mouthrinse usage. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Streptococcus mutans CFU | change from baseline in CFU counts at two weeks | data collected at the begining of the study and two weeks after mouthrinse usage. |
| Lactobacillus CFU | change from baseline in CFU counts at two weeks | data collected at the begining of the study and two weeks after mouthrinse usage. |
| Aerobic and anaerobic oral bacteria CFU | change from baseline in CFU counts at two weeks | data collected at the begining of the study and two weeks after mouthrinse usage. |
Countries
Portugal
Outcome results
None listed