Kidney Failure, Chronic
Conditions
Keywords
Exercise Tolerance, Physical Endurance
Brief summary
The investigators raised the hypothesis that exercise training would be associated with improvement in exercise tolerance and VO2 kinetics in hemodialysis patients.
Detailed description
End-stage renal disease (ESRD) is associated with several hemodynamic and peripheral muscle abnormalities which could slow the kinetics of O2 uptake(VO2)and diminished tolerance to incremental exercise. Although previous studies have shown that aerobic training is able to accelerate VO2 kinetics in several disease populations, little is known if these positive findings are also applicable to hemodialysis patients.
Interventions
OTHERExercise training
Patients included in the exercise group were submitted to intra-dialytic exercise training, 3 times per week for 12 weeks.
Sponsors
Federal University of Juiz de Fora
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
The sample included end stage renal disease patients undergoing hemodialysis, three times per week totaling 12h weekly, for at least 6 months in the Nephrology Unit at the University Hospital of the Federal University of Juiz de Fora, State of Minas Gerais, Brazil. No patient had been involved in any kind of exercise training in the preceding 6 months
Exclusion criteria
* unstable angina; * uncontrolled arrhythmia; * uncompensated heart failure; * uncontrolled hypertension (systolic blood pressure ≥ 200 mmHg and/or diastolic blood pressure ≥ 120 mmHg); * diabetes mellitus; * severe respiratory diseases; * acute infection; * severe renal osteodystrophy; * neurological or musculoskeletal disturbances
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of aerobic training during hemodialysis on exercise tolerance and VO2 kinetics in end stage renal disease patients | 3 months | Before and after the intervention or control periods, the participants were submitted to an incremental work rate test and, two days apart, to a constant work rate test to the limit of tolerance. |
Countries
Brazil
Outcome results
None listed