Healthy
Conditions
Keywords
Adult, Women, Dietary Fiber, Satiety Response, Food Intake
Brief summary
Studies have found a relationship between dietary fiber consumption and body weight regulation. This relationship may stem from enhanced satiety through fermentation of certain fibers in the large intestine. The objective of this study is to determine and compare satiety ratings, changes in food intake, and gastrointestinal effects for four fibers: fructooligosaccharide, inulin, soluble corn fiber, and resistant starch.
Interventions
DIETARY_SUPPLEMENTControl
Dinner bar fortified with 0g fiber; breakfast bar fortified with 0g dietary fiber.
DIETARY_SUPPLEMENTSoluble corn fiber
Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.
DIETARY_SUPPLEMENTResistant starch
Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.
DIETARY_SUPPLEMENTFructooligosaccharide
Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.
DIETARY_SUPPLEMENTInulin
Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy women * Age 18-40 years * Nonsmoking * Not taking weight loss medications * Non-dieting (weight has not changed more than 11 pounds over three months) * BMI between 18.5 and 29 * Spoken and written English literacy
Exclusion criteria
* Do not regularly consume breakfast * Food allergies to wheat, soy, peanut, or dairy * BMI less than 25 or greater than 29 upon admission to study * Cancer diagnosis in past 5 years * History of heart disease, kidney disease, diabetes, or eating disorder * History of ulcerative colitis, Crohn's disease, or any other gastrointestinal condition * History of drug or alcohol abuse in past 6 months * Use of lipid-lowering, anti-hypertensive, or anti-inflammatory steroid medication * Concurrent or recent (within 30 days) intervention study participation * Pregnant or lactating * Irregular menstrual cycle * Vegetarians * People who eat more than approximately 15 grams of fiber per day
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Satiety response using visual analogue scales | 0, 15, 30, 45, 60, 90, 120, 180 minutes postprandially | Satiety response will be measured using subjective perceptions of hunger, fullness, satisfaction, and prospective food intake evaluated by previously validated visual analogue scales (VAS). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Food intake | 180 minutes postprandially and over 24 hours | — |
| Breath hydrogen response | 0 and 180 minutes | — |
| Gastrointestinal tolerance using visual analogue scales (VAS) | 24 hours | Subjective ratings of bloating, stool consistency, and flatulence will be measured using VAS. A stool count will also be recorded. |
Countries
United States
Outcome results
None listed