Proiriftrative Diabetic Retinopathy
Conditions
Brief summary
Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly. However , the treatment may also resulting adverse effects such as blurring of central vision, visual field constriction and disturbance in dark adaptation and contrast vision. Extended targeted retinal coagulation (TRP) to the ischemic areas may cause regression of the neovascularization while minimizing some of the risks and complication associated of treatment of PDR with these two methods.
Interventions
PROCEDUREconventional prp
pan retinal photocoagulation
PROCEDUREtargeted prp
1200-1600 spot in far periphery retin, anterior equator
Sponsors
Shahid Beheshti University of Medical Sciences
Study design
Allocation
RANDOMIZED
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients with PDR condidate for photocoagulation teraphy * Pupil with dilatasion≥6mm * without privious treatment with anti VEGF drugs 3months before study * without privious vitroretinal sugery * without privoius lasertraphy
Exclusion criteria
* To have NVI cricteria with increase of inraocular pressure * to have cataract or vitrus leakage which prevent lasertraphy * pupil smaller that 6mm * traditional retinal detachment * privious treatment with anti VEGF drugs 3months before study * privious PRP * patient unable to get wide field FAG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| no leakage in widefield fluorescin angiography | 3 months after lasertraphy |
Countries
Iran
Outcome results
None listed