The Impact of Obesity on Children and Adolescents.

The Relation of Obesity With Metabolic Disorders, Inflammation Markers and Arterial Blood Pressure With Preclinical Target-organ Damage in Children and Young Adolescents.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01231152

Enrollment

Registered

2010-11-01

Start date

2010-09-30

Completion date

2012-12-31

Last updated

2012-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Risk Factors, Obesity

Brief summary

The aim of the study is to investigate the association of obesity with arterial blood pressure, atherosclerosis, target organ damage (heart, arteries, kidney) and insulin resistance in children and young adolescents.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

8 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Overweight (85th\<BMI\<95th percentile) and obese (BMI\>=95th percentile) children and adolescents * No medication treatment (apart from bronchodilators, T4 in euthyroid children) * No severe mental problem * Parents' and patients' signed consent

Exclusion criteria

* Severe chronic or acute cardiac disease or other severe chronic or acute disease * Any acute inflammation * Familial dyslipidemia * Clinical hypothyroidism or other endocrinopathy * Poor compliance.

Design outcomes

Primary

Measure	Time frame
Blood Pressure levels, Target organ damage (Left Ventricular Hypertrophy, IMT, pulse wave velocity, microalbuminuria), Insulin Resistance	3 weeks

Countries

Greece

Outcome results