Colonic Inertia
Conditions
Keywords
fiber, calcium, magnesium
Brief summary
To compare calcium and magnesium absorption within subjects with and without chronic consumption of wheat dextrin.
Interventions
DIETARY_SUPPLEMENTwheat dextrin
5 grams of wheat dextrin baked in cookies will be taken 3 times a day for 2 weeks
DIETARY_SUPPLEMENTplacebo
cookies not containing wheat dextrin will be taken 3 times a day for 2 weeks
Sponsors
Novartis
Creighton University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
\- Subjects will be generally healthy Caucasian females aged 19 and older with no known abnormalities of gastrointestinal function, and taking no medications that might alter absorptive performance. BMI will be between 19 and 31 kg/m2 \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Calcium Absorption | within 2-4 weeks | The calcium load to be tested will be 300 mg calcium from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with ≈3-7 μCi of 45Ca. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Magnesium absorption | within 2-4 weeks | The magnesium load to be tested will be from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with 30 mg 26Mg. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast. |
Outcome results
None listed