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New Echocardiographic Methods for Right Ventricular Function.

Evaluation of New Echocardiographic Methods for Measurement of Right Ventricular Function.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01230294
Acronym
NEW-RV
Enrollment
150
Registered
2010-10-29
Start date
2010-10-31
Completion date
Unknown
Last updated
2016-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Right Ventricular Dysfunction

Keywords

echocardiography of the right heart, 3D 4D echocardiography, strain measurement, chronic heart failure, pulmonary hypertension

Brief summary

Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function .

Detailed description

Studies of the last years revealed that the right ventricular function is an important predictive value for the survival of patients with congenital heart disease, pulmonary hypertension or chronic heart failure. In 2006 the National Heart, Lung and Blood Institute has pronounced the right ventricular dysfunction including the non-invasive assessment of the right ventricular function as preferential aim of cardiovascular research. Many parameters are used to describe right ventricular dysfunction, but none of these has a comparable significance like the left ventricular ejection fraction. Because of the limitation of each right ventricular parameter the stepwise combination of these parameters is used to describe right ventricular function what frequently results in further problems, especially in comparison of long-term controls. Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function. The study is carried out as prospective, monocentric trial at the Department of Cardiology of the University Hospital of Heidelberg. Three different groups are set up for the assessment of the right ventricular function: patients with pulmonary arterial hypertension, patients with chronic heart failure of the left ventricle affecting the right heart and patients without structural heart disease who underwent an echocardiographic examination for other reasons (control group). All participants are re-examined in constant intervals as clinically indicated.

Interventions

None listed

Sponsors

Heidelberg University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* persons of 18 years and older who receive a transthoracic echocardiography at our department * written consent

Exclusion criteria

* present atrial fibrillation/flutter * permanent pacemaker rhythm * moderate/severe valvular heart disease * pregnancy

Design outcomes

Primary

MeasureTime frame
3D-volumetry of the right ventricle2 years
2D strain of the right ventricle2 years

Secondary

MeasureTime frameDescription
tricuspid annular systolic velocity (TASV)2 yearsstandard value: ≥ 20cm/s
pulmonary artery systolic pressure (PASP)2 yearsstandard value: ≤ 30 mmHg
LV-eccentricity-index (Lei-index)2 yearsstandard value: ≥ 1,0
Tei-index (myocardial performance index)2 yearsstandard value: ≥ 0,5
tricuspid annular plane systolic excursion (TAPSE)2 yearsstandard value: ≥ 20 mm

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026