Respiratory Tract Infections [C08.730]
Conditions
Brief summary
The purpose of this study is to evaluate the symptom impact of probiotic Lactobacillus rhamnosus GG during rhinovirus infection.
Interventions
OTHERFruit juice with Lactobacillus rhamnosus GG, version 1
OTHERFruit juice with Lactobacillus rhamnosus GG, version 2
OTHERStandard fruit juice
Sponsors
University of Helsinki
University of Virginia
Medcare Ltd
Valio Ltd
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Male or female in general good health (stabilized chronic illnesses and regular medications are accepted, if not otherwise mentioned in the
Exclusion criteria
) 2. Age 18-65 years 3. Serum neutralizing antibody titer of 1:4 or less for the challenge rhinovirus 4. No clinically significant finding on the pre-study nasal examination 5. Females must have a negative urine pregnancy test, and women of child-bearing potential must be using an effective method of birth control such as, but not limited to birth control pills, contraceptive foam, diaphragm, IUD, surgical sterilization, abstinence, or condoms 6. Written informed consent must be obtained at enrollment into the study
Countries
United States
Outcome results
None listed