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Prospective Study of the Impact of Systemic Corticosteroid Use on Measures of Sleep Disordered Breathing

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01228695
Enrollment
20
Registered
2010-10-26
Start date
2007-01-31
Completion date
2010-01-31
Last updated
2010-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Apnea

Keywords

steroids, patients treated with systemic steroids

Brief summary

Weight gain is both a significant risk factor for obstructive sleep apnea and a side-effect of long-term systemic steroids therapy. This study aimed to investigate the impact of long-term systemic steroid treatment on sleep apnea.

Interventions

The polysomnography (PSG) (Alice 3 System; Healthdyne, Atlanta, GA) consisted of continuous polygraphic recording from surface leads for electroencephalography, electrooculography, electromyography, electrocardiography, thermistors for nasal and oral airflow, thoracic and abdominal impedance belts for respiratory effort, pulse oximeter for oxyhemoglobin level, tracheal microphone for snoring, and sensors for leg and sleep position

Sponsors

Israeli association for lung disease
CollaboratorUNKNOWN
Rambam Health Care Campus
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* For inclusion, a scheduled therapy with a minimum daily dose of 10 mg prednisone (or equivalent) for at least 3 months was required

Exclusion criteria

* Patients younger than 18 years and those with known sleep apnea or other forms of sleep-disordered breathing were excluded

Design outcomes

Primary

MeasureTime frame
apnea-hypopnea index3 months

Secondary

MeasureTime frameDescription
sleep study variables3 monthsapnea-hypopnea interval desaturation at the end of apnea interval snoring intensity

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026