Single Embryo Transfer vs. Double Embryo Transfer in an Oocyte Donation Programme

A Prospective, Randomized, Controlled Trial Comparing SET vs DET in an Oocyte Donation Programme

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01228474

Enrollment

Registered

2010-10-26

Start date

2010-10-31

Completion date

2012-12-31

Last updated

2015-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cumulative Pregnancy Rate, Infertility, Multiple Pregnancy, Oocyte Recipient, Single Embryo Transfer/Double Embryo Transfer

Brief summary

Experimental study to assess the efficacy of single embryo transfer (SET) with respect to double embryo transfer (DET) in an oocyte donation programme, 160 recipients will be randomized in two groups

Interventions

OTHERSelect the Number of embryos to transfer

Select the Number of embryos to transfer

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* patients under their first or second cycle of a synchronous donation * to have a minimum of 5 available embryos to transfer * patients who accept transfers of frozen-thawed embryos

Exclusion criteria

* medical indications to transfer only one embryo (Turner Syndrome, uterine surgical history, uterine myomas,…)

Design outcomes

Primary

Measure	Time frame
Cumulative pregnancy rate	at 12 months of fresh embryo transfer (time considered enough in order to do a minimum of one frozen-thawed cycle if pregnancy is not achieved with the fresh cycle

Secondary

Measure	Time frame
Cumulative live birth rate	—
Multiple pregnancy rate	—
Time needed to achieve the pregnancy	—

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026