Dry Eye
Conditions
Keywords
Dry eye
Brief summary
The effect of artificial tears on tear osmolarity
Detailed description
Tear osmolarity measures the amount of solutes in the human tear film. The higher the reading, the more likely the patient has dry eyes. Some say it has potential to be the gold standard of dry eye testing. The investigators study the tear osmolarity at different time points after instillation of artificial tears.
Interventions
DRUGArtificial tears
Instill one drop of artificial tears
Sponsors
Allergan
Hom, Milton M., OD, FAAO
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Between the ages of 18 and over inclusive. Males or females Any race or ethnic background Patient is in generally good & stable overall health. Patient likely to comply with study guidelines & study visits. Informed consent signed. Subjective evaluation of symptom of dryness (SESoD): Score 2 (Mild) \-
Exclusion criteria
Corneal refractive surgery within 6 months of this study. Intra-ocular surgery within 6 months or ocular laser surgery within 6 months. Pregnant or lactating women. Ocular pathology (includes glaucoma and cataract), which could impact results and/or place patient at risk. Corneal staining Grade 3 or higher No Restasis for past 3 months Discontinue topical medications for at least 1 week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tear osmolarity | 2 days | Tear osmolarity measured with TearLab instrument |
Countries
United States
Outcome results
None listed