NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure

Plasmatic Level of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Predictive Marker of Acute Kidney Failure in Patients With Preoperative Chronic Kidney Failure Undergoing Cardiac Surgery.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01227122

Acronym

NGAL-CKF

Enrollment

100

Registered

2010-10-25

Start date

2010-08-31

Completion date

2013-09-30

Last updated

2013-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgical Procedures, Postoperative KIDNEY FAILURE, ACUTE, Preoperative KIDNEY FAILURE, CHRONIC

Keywords

NGAL plasmatic level, Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE, Cardiac Surgery Procedures

Brief summary

Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure Secondary endpoint is to obtain threshold values of NGAL.

Detailed description

(N/A)

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Renal clearance less than 60 mL/min * Able to give written consent * Elective valve surgery * Elective CABG surgery

Exclusion criteria

* Less than 18 years old * Iodine injection within 3 days before surgery * Iodine injection within 24 first postoperative hours * preoperative infection * evolutive cancer disease * Refusal * Pregnancy * Unable to give written consent

Design outcomes

Primary

Measure	Time frame
Neutrophil Gelatinase Associated Lipocalin (NGAL) level	From surgery to discharge from hospital

Countries

France

Outcome results