Self Medication With Oral Morphine After Total Knee Arthroplasty.

Self Medication With Oral Morphine After Total Knee Arthroplasty. A Randomised Controlled Trial Comparing Self Medication With Standard Nurse Dispensing. Is There a Difference in Morphine Consumption, Pain, Patient Satisfaction or Safety?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01226186

Enrollment

144

Registered

2010-10-22

Start date

2010-10-31

Completion date

2011-06-30

Last updated

2012-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthroplasty, Knee Replacement, Pain Control

Keywords

Knee replacement, Pain control, Self medication

Brief summary

The study aims to compare two post operative pain management strategy's, traditional nurse dispensed pain control versus patient self medication. The investigators aim to establish if patients who self medicate have differing pain levels than those who take nurse dispensed oral morphine.

Interventions

BEHAVIORALNurse dispensed oral morphine.

Nurse will dispense oral morphine on request from the patient.

BEHAVIORALPatient self medication of oral morphine.

Patients will self medicate their oral morphine pain control solution following surgery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients requiring total knee replacement surgery willing to provide written, informed consent.

Exclusion criteria

* Unable to safely self medicate. Allergy to morphine. Unable to provide consent. Contraindication to the standardised anaesthetic or standard postoperative care. Not consenting to an element of the standardised anaesthetic. Pre-operative use of strong opiates e.g. Oramorph, MST, Oxynorm.

Design outcomes

Primary

Measure	Time frame
To establish if patients who self medicate with oral morphine have differing pain levels than those who take nurse dispensed oral morphine.	one year

Secondary

Measure	Time frame
To identify if patients who self medicate with oral morphine take a significantly different amount of morphine compared with those who take nurse dispensed oral morphine.	one year
To compare whether patients who self medicate with oral morphine have a significantly altered level of side effects compared with those who take nurse dispensed oral morphine.	one year

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026