Pilot Randomised Controlled Trial of Posturing Following Surgery for Full-thickness Macular Hole

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01226160

Enrollment

Registered

2010-10-22

Start date

2005-01-31

Completion date

2010-10-31

Last updated

2010-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Full Thickness Macular Hole

Brief summary

This is a pilot randomised controlled trial (RCT) to investigate the effect of postoperative face-down positioning on the outcome of macular hole surgery.

Interventions

PROCEDUREPostoperative face-down posturing

Postoperative face-down posturing for 10 days after surgery.

PROCEDUREPostoperative non-posturing group

avoid a face-up position only for 10 days after surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

* full thickness macular hole * \>16 years old

Exclusion criteria

* any history of previous intraocular surgery (including cataract surgery) * history of ocular trauma * history of visual loss greater than 1 year

Design outcomes

Primary

Measure	Time frame
Anatomical closure of the macula hole assessed 6 weeks following surgery by ocular coherence tomography.	6 weeks

Secondary

Measure	Time frame
Visual acuity assessed 6 weeks following surgery by Snellen charts.	6 weeks

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026