Pulmonary Complications of Allografts

Prospective Cohort Study of Late Pulmonary Complications in Patients Who Received Allogeneic Hematopoietic Stem Cells Transplantation: Estimation of Incidence and Identification of Distinct Nosologic Entities

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01219972

Acronym

ALLOPULM

Enrollment

245

Registered

2010-10-13

Start date

2006-01-31

Completion date

2016-12-31

Last updated

2017-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Complications

Keywords

Bone marrow transplant, Pulmonary complications

Brief summary

This is a prognostic study of the late lung complications arising at the patient's having received an allograft of hematopoetic stem cells.

Detailed description

* Objectives To estimate the incidence of late (at least occurring 100 days after transplantation) pulmonary complications following allogeneic blood stem cells transplantation * Study Design Prospective Cohort Study All follow-up data were actualiized in September, 2016. * Sample Size 200 transplanted patients * Main Endpoint Non infectious pulmonary complications within the first 3 years

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Allogeneic Blood stem cell transplantation * Alive at day 100 post-transplant

Exclusion criteria

* Non informed consent

Design outcomes

Primary

Measure	Time frame
Non infectious pulmonary complication	3 years

Secondary

Measure	Time frame
Survival after non infectious pulmonary complication	3 years and 10 years
Overall survival	3 years and 10 years
Long term time course of Pulmonary Function Tests (PFTs)	3 years and 10 years

Countries

France

Outcome results