Subarachnoid Hemorrhage
Conditions
Keywords
subarachnoid hemorrhage, scintigraphy, neurocardiogenic injury
Brief summary
The aim of this study is to describe acute neurocardiogenic injury after subarachnoid hemorrhage assessed with cardiac 123I-MIBG scintigraphy and 18F-FDG PET/CT during the first week and the first six months after SAH. The study hypothesis is that the evolution of the cardiac disturbances follows the clinical evolution.
Detailed description
The cardiac metabolic disturbance are assessed by a 18F-FDG PET/CT in the first week after SAH and monthly until normal result. The myocardial sympathetic innervation is assessed by a cardiac 123I-MIBG scintigraphy in the first week after SAH and six months later. Clinical outcome is assessed by Glasgow Outcome Scale, modified Rankin Scale and MOS-SF36 at 1, 3 and 6 months after SAH.
Interventions
None listed
Sponsors
Direction Centrale du Service de Santé des Armées
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age * SAH * Hospitalization in the Military Teaching Hospital Sainte Anne
Exclusion criteria
* Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiac 18F-FDG PET | first week after SAH |
Secondary
| Measure | Time frame |
|---|---|
| cardiac 123I-MIBG scintigraphy | first week after SAH |
| cardiac 18F-FDG PET | one month after first cardiac 18F-FDG PET |
Countries
France
Outcome results
None listed