The Role of Mechanical Stress and Muscle Fatigue in Strength Gains

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01216774

Enrollment

Registered

2010-10-07

Start date

2010-09-30

Completion date

Unknown

Last updated

2012-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Strength, Muscle Mass, Inflammatory Processes, Strength Training

Brief summary

The purpose of this study is to compare the impact of different levels of mechanical stress and muscle fatigue in strength training conditions on muscle strength, muscle mass and inflammatory processes.

Interventions

OTHERStrength training

Leg extension exercise: Experimental: 60 repetitions at 20-25% of 1RM, 10-12 repetitions at 40% of 1RM Active Comparator: 10-12 repetitions at 80% of 1RM Placebo Comparator: 10-12 repetitions at 40% of 1RM

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

20 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

Exclusion criteria

* Knee pathology * Systematic training

Design outcomes

Primary

Measure	Time frame
Force-velocity characteristics of knee extensors with biodex dynamometer	Pre and post intervention

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026