Pulmonary Embolism and Stroke in Patient With Patent Foramen Ovale

Is There a Link Between Venous Thromboembolism and Stroke in Patient With Patent Foramen Ovale ? Research for Stroke in Hospitalized Patients With Pulmonary Embolism.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01216423

Acronym

EPIC-FOP

Enrollment

374

Registered

2010-10-07

Start date

2009-11-30

Completion date

2017-01-31

Last updated

2017-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent Foramen Ovale, Pulmonary Embolism, Recent Stroke

Keywords

Patent Foramen Ovale, Pulmonary embolism, Stroke

Brief summary

The cause of ischemic stroke remains frequently unknown. In patients with patent foramen ovale (PFO), the link between PFO and Stroke is unclear. The investigators hypothesize that the main mechanism is paradoxical embolism and decided to look for clinically apparent and silent cerebral embolism in patients with a recent pulmonary embolism.

Detailed description

Inclusion criteria : * age \> 18 years old * confirmed pulmonary embolism * informed consent * social ensured Exclusion criteria : * pregnancy * age \< 18 years old * protected major person (in sense of public health) * consent refused * MRI contraindications

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 years old * confirmed pulmonary embolism * informed consent * social ensured

Exclusion criteria

* pregnancy * age \< 18 years old * protected major person (in sense of public health) * consent refused * MRI contraindications

Design outcomes

Primary

Measure	Time frame
Incidence of recent ischemic stroke in patients hospitalized for a recent pulmonary embolism with comparison in two groups with and without PFO	7 days

Countries

France

Outcome results