Estimation of Glomerular Filtration Rate (GFR) in Patients With Type 2 Diabetes Mellitus.

Comparative Study of New Formulae of GFR Estimation Based on Creatinine, Cystatin C and Cr51-EDTA.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01215994

Enrollment

600

Registered

2010-10-07

Start date

2009-03-31

Completion date

2016-03-31

Last updated

2015-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus, Diabetic Nephropathy

Brief summary

The purpose of the present study is to evaluate bias, precision and accuracy of new cystatin C and creatinine based equations for GFR estimation compared with 51Cr-EDTA (chromium-51 labeled ethylenediamine tetraacetic acid) measured GFR in patients with diabetes.

Detailed description

The purpose of the present study is to evaluate bias, precision and accuracy of new cystatin C and creatinine based equations for GFR estimation compared with 51Cr-EDTA measured GFR in patients with diabetes. Additional, we will check which equation detects better the reduction of renal function over the time, in patients with diabetes. Finally, we will investigate if cystatin C levels can be influenced by factors other than GFR

Interventions

None listed

Study design

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Type 2 and type 1 diabetes mellitus

Exclusion criteria

* Patients with other type diabetes: gestational, exocrine pancreatic defects, endocrinopathies, drugs * Patients with end-stage renal disease, cardiac failure, hepatic failure, malignancies, immunosuppression, pregnant, diabetic ketoacidosis

Countries

Greece

Contacts

Primary ContactFotios Iliadis, MD, PhD

iliadis@med.auth.gr2310993472

Outcome results