Obstructive Sleep Apnea Syndrome
Conditions
Keywords
Randomized controlled study, Exercise training, Lung function, Heart function
Brief summary
The purpose of this study is to investigate if 3 months of interval training improves obstructive sleep apnea in obese patients diagnosed with moderate to severe obstructive sleep apnea. The working hypothesis is that 3 months of 3 weekly aerobic interval training sessions improve obstructive sleep apnea and sleep quality in obese patients.
Detailed description
Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive obstruction and collapse of the upper airway resulting in successive episodes of cessation of or decreased respiratory airflow, causing oxygen desaturation, awakening, loud snoring and daytime sleepiness in patients. Sleep apnea is frequently associated with co-morbidity such as obesity, diabetes, hypertension, the metabolic syndrome and cardiovascular disease. Lack of exercise is associated with OSAS severity, independent of body mass. Participation and motivation to exercise is low in OSAS patients, with less that one third of the patients reporting regular exercise routines. We aim to investigate if aerobic interval training improves OSAS in obese subjects.
Interventions
Treadmill walking or running - 3 times per week for 3 months. The interval training session consists of 10 minutes warm up and continues with 4 x 4 minutes high intensity intervals at 90-95% of maximal heart rate. Training intensity will be supervised through the use of Polar pulse monitors and the BORG scale of subjective perceived exhaustion.
Standard medical treatment
Sponsors
Study design
Eligibility
Inclusion criteria
* BMI ≥ 30 kg/M2 * Apne - hypopnea index (AHI) \> 10 * No significant comorbidities * Abel to exercise
Exclusion criteria
* Inability to exercise due to musculoskeletal conditions * Known ischemic cardiovascular disease * Drug abuse * Mental illnesses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Apnea-hypopnea index change | Baseline, 3 and 6 months | Measured by Polysomnography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sleep quality | Baseline, 3 and 6 months | Epworth Sleepiness Scale |
Countries
Norway