Diabetes Mellitus
Conditions
Keywords
Diabetes Mellitus, HbA1c, Glycation Rate, Fructosamine
Brief summary
HbA1c is used as a gold standard to see whether patients have optimal glycemic control. Today, many physicians rely solely on HbA1c to change medication. However, there is a select group of patients that have low average glucose levels but high HbA1c levels. The investigators believe that these patients are fast glycators meaning that they incorporate sugar into their hemoglobin faster than normal. The investigators want to determine whether these patients are fast glycators.
Interventions
OTHERFast Glycator
The subjects enrolled in this study will have a fructosamine test and blood drawn to see whether they are fast glycators
OTHERControl
These patients will have their blood drawn to know what the normal glycation rate is in diabetic patients
Sponsors
Endocrine Research Society
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patient with diabetes * Patients who test their sugar levels at least 3 times daily * Recorded diary of sugar levels for the past month * Willingness to have blood drawn * Willingness to allow their blood sugar diary to be photocopied * Estimated average glucose as derived from A1c is ≥ 4 mmol from measured glucose from self-monitoring blood glucose testing
Exclusion criteria
* Patient with medical conditions that may affect their study participation or results will be excluded. * Patients who are anemic * Renal insufficient with a serum creatinine level \> 200 μmol/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint is to see whether they are fast glycators | One Week |
Secondary
| Measure | Time frame |
|---|---|
| A secondary endpoint includes adverse events such as unplanned hospitalizations for any cause that last more than 24 hours | One Week |
Outcome results
None listed