Complex Aortic Surgery
Conditions
Brief summary
This proposal is for the pilot study that will inform the conduct of a larger prospective randomized controlled trial to guide perioperative work up and the cost/utility of CTCA (high definition CT coronary angiography.)
Detailed description
This proposal is for a pilot study that will inform the conduct of a prospective, blinded randomized controlled trial designed to determine the cost effectiveness of an algorithm for pre operative cardiac risk stratification that uses coronary CT angiography. In addition perioperative and long-term cardiac event rate will be recorded to determine if there is any difference in these rates between the 2 groups.
Interventions
OTHERcontrast CTA of the CAP
CT coronary angiography results will be reported for all patients by adjudicators blinded to their inclusion in the study.
Sponsors
The Cleveland Clinic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients being considered for a complex aortic surgery and undergoing medically indicated contrast enhanced CT aortic angiography of the chest abdomen and pelvis
Exclusion criteria
* Patients with contraindications to undergoing CT coronary angiography * coronary revascularization within the last six months * renal dysfunction in whom the treating physician has decided a contrast enhanced CT scan is not warranted as part of the routine clinical work up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome for the pilot study will be to assess feasibility of processes as set out in the specific aims. | 6 months |
Outcome results
None listed