Epilepsy, Movement Disorders
Conditions
Keywords
All indication for deep brain stimulation (DBS)
Brief summary
Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement. The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires. * Trial with surgical intervention
Detailed description
Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement. The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.
Interventions
PROCEDUREdeep brain stimulation (DBS)
deep brain stimulation (DBS) is in itself not part of this study but a clinical indication. The study aims at documenting DBS parameters and outcome
Sponsors
University of Zurich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients fullfill all criteria for implantation of deep brain stimulation (DBS) electrodes * Patients are able to give informed written consent
Exclusion criteria
* Patients do not their give informed written consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| neurological outcome | 5 years | UPDRS |
Countries
Switzerland
Outcome results
None listed