Sarcoma
Conditions
Keywords
Ewing sarcoma, Ewing sarcoma/peripheral primitive neuroectodermal tumor (PNET)
Brief summary
RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.
Detailed description
OBJECTIVES: * To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients. OUTLINE: This is a multicenter study. Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.
Interventions
Sponsors
Institut Curie
Study design
Observational model
FAMILY_BASED
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to 120 Years
Healthy volunteers
Yes
Inclusion criteria
DISEASE CHARACTERISTICS: * Patients with Ewing sarcoma * Relatives of Ewing sarcoma patients PATIENT CHARACTERISTICS: * Patients with a fusion genes specific of Ewing Sarcoma PRIOR CONCURRENT THERAPY: * Not applicable
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identification and characterization of susceptibility genes in patients with Ewing sarcoma | Through study completion, an average of 10 years | Identification and characterization of susceptibility genes in patients with Ewing sarcoma |
Countries
France
Outcome results
None listed