Type Distribution of Human Papillomavirus in Adult African Women Diagnosed With Invasive Cervical Cancer

Human Papillomavirus (HPV) Type Distribution in Adult African Women Diagnosed With Invasive Cervical Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01207999

Enrollment

591

Registered

2010-09-23

Start date

2007-10-31

Completion date

2010-03-31

Last updated

2012-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer, Infections, Papillomavirus

Keywords

Human papillomavirus

Brief summary

The aim of the study is to assess the distribution of the most frequent types of human papillomavirus in African women diagnosed with invasive cervical cancer.

Interventions

PROCEDURECollection of cervical cancer tissue samples

Cervical samples will be tested for histopathology diagnosis and human papillomavirus DNA testing.

OTHERData collection

Questionnaire completion

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* A female aged 21 years or more, presenting with a lesion macroscopically suggestive of invasive cervical cancer. * Scheduled for cervical biopsy as per routine procedure at the participating institution on the day of the visit or on a later date. * Written or oral-witnessed informed consent obtained from the subject prior to any study procedure. * No prior chemo- or radiotherapy for cervical cancer.

Exclusion criteria

Not applicable

Design outcomes

Primary

Measure	Time frame
Occurrence of any of the human papillomavirus types (HPV-16, 18, 31, 33, 35, 45, 52 and 58) among the women diagnosed with invasive cervical cancer	Average time frame: 6-12 months
Occurrence of any of the human papillomavirus types (human papillomavirus-16, 18, 31, 33, 35, 45, 52 and 58) among the women diagnosed with squamous cell carcinoma	Average time frame: 6-12 months

Secondary

Measure	Time frame
Proportion of squamous cell carcinoma cases versus adenocarcinoma and other histologic tumour types of invasive cancer among the women diagnosed with invasive cervical cancer	Average time frame:6-12 months

Countries

Ghana, Nigeria, South Africa

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026