Optimized Radiological Diagnosis of Hepatic Candidiasis During the Treatment of Acute Leukemias

Verbesserung Der Radiologischen Diagnose Von Hepatolienaler Candidiasis während Der Therapie Der Leukämie

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01207843

Enrollment

Registered

2010-09-23

Start date

2009-10-31

Completion date

2013-05-31

Last updated

2014-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection, Leukemia

Keywords

Computed tomography

Brief summary

Hepatic candidiasis is a frequent complication in patients receiving intensive chemotherapy for acute leukemia. Hepatic lesions may be detected by computerized tomographic (CT) scans, but there is no standardized CT protocol for the diagnosis and follow-up of hepatic candidiasis. The investigators compared the size of the fungal lesions in the chest and abdomen CT. The current analysis aimed to increase the value of CT for the diagnosis and the follow-up of hepatic candidiasis in daily routine.

Interventions

BEHAVIORALImaging

CT image validation and lesion measurement, as well as comparison of different CT phases

Study design

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Chest and Abdomen CT with fungal lesion in patients with leukemia

Exclusion criteria

* Other liver pathologies

Design outcomes

Primary

Measure	Time frame
The primary end-point was IFI according to the EORTC/MSG 2008 definitions and bacteraemia	2 Years

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026