Immunological Changes Through Narrative Treatment of Post-Traumatic Stress Disorder (PTSD) in Torture Victims

Immunological Changes Through Narrative Treatment of PTSD in Torture Victims

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01206790

Enrollment

Registered

2010-09-22

Start date

2009-06-30

Completion date

2012-01-31

Last updated

2012-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PTSD

Keywords

PTSD, Narrative Exposure Therapy, torture victims, immune system

Brief summary

Posttraumatic stress disorder (PTSD) is associated with poor health, high health care utilization, and an increased risk for a variety of somatic, inflammatory and autoimmune diseases. Research, including our own findings, indicates immunological alterations in PTSD patients. The aim of this study is to investigate whether alterations in the immune system of PTSD patients are reversible through a trauma-specific short-term therapy (Narrative Exposure Therapy).

Interventions

BEHAVIORALNET

Narrative Exposure Therapy for traumatized survivors of organized violence

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

16 Years to 60 Years

Healthy volunteers

Inclusion criteria

* PTSD diagnosis * experiences of organized violence/torture

Exclusion criteria

* psychotic disorder * chronic inflammatory diseases

Design outcomes

Primary

Measure	Time frame
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)	4 month after completion of treatment

Secondary

Measure	Time frame
changes in immunological parameters	4 months after completion of treatment

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026