Combination Treatment for Moderate to Severe Acne

A Phase IV, Open-Label Study Evaluating the Use of Solodyn (Minocycline HCL Extended-Release Tablets), Ziana, and Triaz Foaming Cloths as Combination Acne Therapy Prior to Treatment With Isotretinoin

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01206348

Enrollment

Registered

2010-09-21

Start date

2010-09-30

Completion date

2011-07-31

Last updated

2011-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne

Keywords

Acne

Brief summary

To determine if a combination of three currently approved acne products are safe and effective for the treatment of moderate to severe acne

Detailed description

A Phase IV, Open-Label Study Evaluating the treatment for Combination Acne Therapy.

Interventions

DRUGMinocycline, Clindamycin, Tretinoin, Benzoyl Peroxide

Solodyn 1 tablet, Q day Ziana Gel, topical Q am Triaz FC, topical Q night

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

12 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* moderate to severe acne, IGA = 3 or 4 (Investigator Global Assessment)

Exclusion criteria

* pregnancy and allergies

Design outcomes

Primary

Measure	Time frame
Proportion of patients showing improvement from Baseline and Week 12	Week 12

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026