Multi-center Registry for CCSVI Testing and Treatment

Status

Suspended

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01205633

Acronym

CCSVI

Enrollment

1000

Registered

2010-09-20

Start date

2010-09-30

Completion date

2015-09-30

Last updated

2012-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CCSVI, Chronic Cerebrospinal Venous Insufficiency, Venous Malformations of CNS Draining Veins

Keywords

neurodegenerative disease, neurovascular disease, fatigue, Hubbard Foundation, angioplasty

Brief summary

Patients suspected of CCSVI (chronic cerebrospinal venous insufficiency) may be tested and if appropriate treated with catheter venoplasty by an interventional radiologist in their local community who has been credentialled either by the local hospital's IRB or a national IRB if the procedure is done in an outpatient facility. Catheter angioplasty is a long-established and accepted medical procedure, patients' insurance should but may not cover the testing or treatment.

Detailed description

more to follow

Interventions

PROCEDUREvenous angioplasty

catheter venous angioplasty via femoral vein approach

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

Referral by patients primary treating physician for suspected CCSVI

Exclusion criteria

Abnormal kidney function Allergy to either or both of the imaging contrast agents Pacemaker or other implantable device Ferrous metal in or on the body Claustrophobia Pregnancy \-

Design outcomes

Primary

Measure	Time frame
Short-Form 36 (SF36) Quality of Life Instrument	Baseline and at 1, 6 and 12 months after treatment

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026