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Mentalization - Based Treatment: Adolescents With Co-morbid Depression and Personality Disorder

Mentalization - Based Treatment for Young People Presenting With Co-morbid Depression and Symptoms of Emerging Personality Disorder: Prospective Controlled Trial.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01204346
Acronym
MBT
Enrollment
75
Registered
2010-09-17
Start date
2010-12-31
Completion date
2016-12-31
Last updated
2014-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Personality Disorder

Keywords

adolescents, MBT, depression, emerging personality disorder

Brief summary

Mentalisation based treatment (MBT) for young people with co-morbid depression and emerging personality disorder will be more effective in a day/inpatient setting than treatment as usual.

Detailed description

Systematic literature review on outcomes with young people with depression and emerging personality disorder showed clear evidence that this group of young people are severely hampered and adult outcomes are strongly linked to both adult PD as well as adult psychiatric disturbance and lower levels of adult functioning. (Crawford et al, 2008; Kasen et al, 1999; Kasen et al, 2007; Lewinsohn et al, 1999) This argues very clearly for the need to diagnose young people presenting with co-morbid depression and emerging personality disorder in order to intervene and help these young people's struggles as it will prevent poor prognostic adult outcomes. There were no treatment programs that specifically focussed on the treatment of this co-morbid group in the literature. Several studies focussed on the treatment of depression alone and only one RCT focussed on the treatment of adolescent personality disorder (Chanen et al, 2007). In adult studies mentalization-based treatment programs were found to be effective ( as well as cost effective) in a day hospital setting for adults with personality disorder and depression (Bateman, et al, 2007) This study aims to conduct a control trial to test whether MBT will be more effective than TAU in this group. All cases will be tested on admission, at discharge and followed up at 2 years post discharge.

Interventions

OTHERMBT

The intervention consists of twice weekly individual MBT therapy, group therapy with an MBT focus and weekly MBFT, which is MBT for families. The treatment duration will be 6-8 weeks.

OTHERtreatment as usual

less intensive and structured psychotherapeutic program

Sponsors

North East London Foundation Trust
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* all young people who are admitted to Brookside adolescent unit between the ages 12 - 17 presenting with depression and emerging personality disorder will be eligible

Exclusion criteria

* Young people with autistic spectrum disorders or severe learning disabilities.

Design outcomes

Primary

MeasureTime frameDescription
Global assessment of functioning2 years post dischargeMeasures global functioning
global assessment of functioningAverage of 8 weeksmeasures level of functioning

Secondary

MeasureTime frameDescription
mood and feelings questionnaire2 years post dischargeAssesses mood in terms of number of depressive symptoms
Mood and feelings questionnaireWithin 1 week of admissionAssesses mood in terms of number of depressive symptoms

Countries

United Kingdom

Contacts

Primary Contacttrudie I Rossouw, Dr
trudie.rossouw@nelft.nhs.uk+448446001200

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026