Testing the Effectiveness of a Computer-based Program for Depression

Attention Training for Major Depressive Disorder

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01203683

Enrollment

Registered

2010-09-16

Start date

2011-01-31

Completion date

2013-10-31

Last updated

2013-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder

Keywords

depression

Brief summary

The purpose of this study is to determine whether completing a computer-based program alters changes how the brain processes emotional information and improves symptoms of depression.

Interventions

BEHAVIORALActive computer-based training

8 sessions across 4 weeks.

BEHAVIORALInert computer training

8 sessions across 4 weeks.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Inclusion criteria

* Major Depressive Disorder

Exclusion criteria

* Substance dependence, psychotic disorder, bipolar disorder, schizophrenia, current psychotherapy, medications other than selective serotonin reuptake inhibitors

Design outcomes

Primary

Measure	Time frame	Description
Beck Depression Inventory-II	Week 4, Week 9	Questionnaire to assess depression symptom severity

Secondary

Measure	Time frame	Description
Structured Clinical Interview for DSM-IV diagnoses	Week 9	Diagnostic interview to assess for presence of Major depressive disorder (MDD).
Neural processing of emotion stimuli	Week 4	fMRI paradigm to assess neural changes in how individuals processes emotional stimuli

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026