Infant, Newborn, Jaundice
Conditions
Keywords
NICHD Neonatal Research Network, Term infant, Hyperbilirubinemia
Brief summary
The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.
Detailed description
Jaundice occurs in most human neonates during the several days after birth. The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.
Interventions
None listed
Sponsors
NICHD Neonatal Research Network
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 8 Hours
Healthy volunteers
Yes
Inclusion criteria
* Infants born via cesarean delivery (to ensure subjects would still be hospitalized and available for ETCOc measurement and blood sampling on day 3 postpartum) * Delivery within each center's scheduled recruitment period (to maximize nursing availability and minimize cost) * Birth weight \>2500 g * Gestational age \>37 weeks
Exclusion criteria
* Any illness that would require admission to the neonatal intensive-care unit (NICU) within 8 hours of birth
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| End-tidal carbon End-tidal carbon monoxide levels corrected for ambient air (ETCOc) | 2-8 hours of age | An index of bilirubin production |
Countries
United States
Outcome results
None listed