Pain
Conditions
Keywords
pain, sucrose, newborn, mechanical ventilation
Brief summary
Evaluate the effectiveness of the use of a 24% sucrose solution for pain management of preterm infants during endotracheal suctioning.
Detailed description
Many infants admitted to neonatal intensive care unit (NICU) undergo repeated invasive procedures. Recent studies have shown that the oral sucrose administration to neonates is safe and effective for pain relief during heel stick and venipuncture.Most data suggest the investigation of the effect of sucrose in other painful procedures such as in ventilated newborns.
Interventions
DRUGsucrose
oral sucrose solution, 24%, 0,5 ml/kg, 2 minutes before start the suctioning sterile water, 0,5 ml/kg, 2 minutes before start the suctioning
Sponsors
Universidade Federal de Pernambuco
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 36 Weeks
Healthy volunteers
No
Inclusion criteria
* preterm infants * over 12 hours of life * intubated * clinically stable * without use of analgesics or sedatives
Exclusion criteria
* preterms with congenital malformations * preterms with genetic syndromes * preterms with Apgar score at 5´\<7 * preterms with meningitis * preterms with diagnosed of necrotizing enterocolitis Ouvir Ler foneticamente
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical pain score | within the first twelve hours after clinical stabilization, the PIPP will be done. | The tool that will be used is PIPP = Premature Infant Pain Profile. This avaliation begins prior to suctioning until 30 seconds after suctioning. Each infant will be avaliated 2 times (with sucrose and with placebo). The 2 avaliations in the same day. |
Countries
Brazil
Outcome results
None listed