Carpal Tunnel Release in Diabetic Patients

Five Years Follow-up After Carpal Tunnel Release in Diabetic and Non-diabetic Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01201109

Enrollment

Registered

2010-09-14

Start date

2010-11-30

Completion date

2011-12-31

Last updated

2010-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome, Diabetes, Nerve Entrapment

Keywords

Carpal tunnel syndrome, Entrapment neuropathies, Diabetes

Brief summary

The aim of this study is to extend a previously reported 1 year follow-up on carpal tunnel release, in matched diabetic and non-diabetic patients,to compare outcomes 5 years after surgery.

Detailed description

The Follow-up investigation includes: 1. Clinical examination of sensory and motor function 2. Generic and disease specific self-administered questionnaires 3. Nerve conduction study 4. Vibration threshold testing

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* diabetic and non-diabetic patients operated for carpal tunnel syndrome 5 years ago.

Exclusion criteria

* previous carpal tunnel release in the hand under study * clinical signs of nerve entrapment other than CTS * cervical radiculopathy, inflammatory joint disease * renal failure * thyroid disorders * previous wrist fracture on the affected side * daily long-term exposure to vibrating tools * pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Patient self-reported outcome questionnaire	5 years after carpal tunnel release	Measured by 1). Boston Carpal Tunnel Questionnaire regarding carpal tunnel symptoms and disability. 2). Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) registering health-related quality of life. 3). Cold intolerance on a CISS score

Secondary

Measure	Time frame	Description
Nerve conduction study and vibrotactile sense	5 years after carpal tunnels release	Change in Median nerve function by measuring Distal motor latency and antidromic sensory conduction velocity over the carpal tunnel segment. Evaluate development of peripheral neuropathy by measure of sural nerve sensory conduction velocity, sural nerve amplitude and peroneal nerve motor conduction velocity. Vibrotactile sense of the hand measured at 7 difference frequences from 5 - 500 Hz.

Countries

Sweden

Outcome results