Efficacy of Topical Capsaicin on Chronic Neck Pain

Efficacy of Topical Capsaicin on Chronic Neck Pain ; Double-blinded Randomized Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01200745

Enrollment

Registered

2010-09-14

Start date

2010-09-30

Completion date

2011-02-28

Last updated

2010-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Neck Pain

Keywords

neck pain, capsaicin, dermal patch

Brief summary

The purpose of this study is to determine whether topical capsaicin patch can effectively reduce chronic neck pain.

Detailed description

* Design: This is a double-blind, randomized, controlled study. Participants: Sixty participants with chronic neck pain are recruited and randomly assigned to two groups. * Intervention: Over an four-week period, the treatment group (n=30) uses capsaicin patch (100 mcg/3cc) at the tender point of neck for 12 hours a day; the control group (n=30) receives Hydrogel patch instead of capsaicin patch.

Interventions

DRUGCapsaicin patch

Over an four-week period, the treatment group (n=30) uses capsaicin patch (100 mcg/3cc) at the tender point of neck for 12 hours a day; the control group (n=30) receives Hydrogel patch instead of capsaicin patch.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Korean participants with Chronic neck pain are enrolled in our study

Exclusion criteria

* Participants with coagulation deficiencies, infections, hypertension, diabetes, heart disease, renal disease, liver disease, cancer, myelopathy, hypersensitivity of drugs, other skeletomuscular disease, allergic response to capsaicin, pregnancy and nursing are excluded

Design outcomes

Primary

Measure	Time frame
Pain Scores on the Visual Analogue Scale(VAS)	4 week

Secondary

Measure	Time frame	Description
Neck disability index	4 week	Neck disability index : questionnaire for measuring how much neck pain affects ability of daily activities
Beck depression inventory	4 week	Beck depression inventory : for assessing depression
SF-36	4 week	questionnaire for measuring health-related quality of life
EQ-5D(EuroQol-5 dimension)	4 week	questionnaire for measuring health-related quality of life

Countries

South Korea

Contacts

Primary ContactYu-Jeong Cho

jamyunghwa@hotmail.com+82-2-440-7575

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026