Obesity
Conditions
Keywords
obesity, metabolic syndrome, fecal fat excretion, fecal calcium, weight loss, appetite regulation, intestinal micro flora, lipid profile, energy balance
Brief summary
The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately overweight men and women over 24 weeks.
Interventions
OTHERHigh Calcium intake from dairy products
High dietary intake of calcium from dairy products (\ 1200 mg/d)
Sponsors
The Ministry of Science, Technology and Innovation, Denmark
The Danish Dairy Research Foundation, Denmark
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* men and women, * medium overweight (body mass index 28-36 kg/m2), * 18-60 years old, * low habitual calcium intake (\<800 mg/d)
Exclusion criteria
* milk allergy, infection diseases and diabetes, * intake of dietary supplements, * smoking, * pregnancy and/or breast feeding, * any medications known to affect the outcome measurements, * weigh reducing diet, * gastrointestinal diseases, * participation in other intervention studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal fat excretion | 24 weeks |
| Body weight | 24 weeks |
| body composition | 24 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Lipid profile | 24 weeks |
| Intestinal micro flora | 24 weeks |
| Metabolomics in urine, feces and blood | 24 week |
| calcium excretion | 24 weeks |
| Resting energy expenditure | 24 weeks |
| vitamin D status | 24 weeks |
| calcium status | 24 weeks |
| lipid metabolism | 24 weeks |
| bone markers | 24 weeks |
| Blood pressure | 24 weeks |
| Appetite regulation | 24 weeks |
Countries
Denmark
Outcome results
None listed