Left Ventricular Hypertrophy
Conditions
Keywords
Fabry-Anderson disease, gen mutation, left ventricular hypertrophy
Brief summary
The purpose of this study is to determine the prevalence of Fabry mutations in patients with left ventricular hypertrophy (moderate to severe), as measured by echocardiography.This study is a screening study
Interventions
OTHERblood sampling
Blood sampling will be used.
Sponsors
University Hospital, Ghent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients over 18 years undergoing a routine echocardiography in the participating hospitals * Both genders will be considered. * Patients can be included if on 2D echocardiography the maximal septal wall thickness \> 13 mm and/or the posterior wall thickness \> 13 mm. The limit for inclusion is kept relatively low to detect early forms of Fabry cardiomyopathy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determination of the prevalence of Fabry mutations in patients with left ventricular hypertrophy (moderate to severe), as measured by echocardiography | At baseline T0 | patients with left ventricular hypertrophy will be screened for Fabry mutations, and results will be communicated within four months |
Countries
Belgium
Outcome results
None listed