Coronary Artery Disease, Diabetes Mellitus
Conditions
Keywords
DM, CAD, Meal tolerance test
Brief summary
To determine the glucose regulation status of patients who were suspected to have CAD in central Taiwan.
Detailed description
It had been reported that high prevalence of IGT (impaired glucose tolerance) and unknown DM (diabetes mellitus) in patients with CAD (coronary artery disease). This study aimed to determine the glucose regulation status of patients who were suspected to have CAD in central Taiwan. In general, patient who were admitted for CAG (coronary angiography) or MDCT without known DM were eligible. After informed consent, OGTT (oral glucose tolerance test) was performed to determine the glucose regulation status. Study participants will be requested to complete questionnaires to assess their risk of diabetes and quality of sleep. Patients who were diagnosed as new DM would be asked to follow up in clinical service with diet control.
Interventions
None listed
Sponsors
Taichung Veterans General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient received CAG or MDCT for suspect CAD * Without DM history
Exclusion criteria
* Known DM * Unstable disease condition * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diabetes | 3 months | Based on OGTT and HbA1c |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Brain-derived neurotrophic factor | 3 months | An biomarker to link brain and atheroclerosis |
| Coroanry artery disease | 3 months | Based on coronary angiography and medical record |
| Mortality | 5 years | All-cause and cardiovascular |
Countries
Taiwan
Outcome results
None listed