Safety Study of Subclavian and Internal Jugular Venous Catheterization

A Randomize Controlled Trial to Compare the Complications of Subclavian and Internal Jugular Venous Catheterization in Critically Ill Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01196962

Enrollment

300

Registered

2010-09-09

Start date

2010-11-30

Completion date

2013-12-31

Last updated

2012-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rates of Complications, Time to Insertion

Keywords

central venous catheter, complications, internal jugular vein, randomized trial, subclavian vein

Brief summary

There is no randomized controlled trial to compare the rates of complications associated with internal jugular and subclavian venous catheterization. The aim of this study is to compare mechanical, infectious, and thrombotic complications of internal jugular and subclavian venous catheterization. An improved understanding of CVC-related risks might help clinicians to choose one approach over the other in specific clinical settings.

Detailed description

Central venous catheterization is often necessary to treat critically ill patients hospitalized in intensive care units (ICUs). However, this procedure may lead to serious and sometimes life-threatening complications, including mechanical, infectious, or thrombotic complications. The choice of insertion site can influence the incidence and type of such complications. The most frequently used sites for CVC insertion are the internal jugular and the subclavian vein. However, in an individual patient, criteria for choosing one approach over the other remain unclear.

Interventions

DEVICECentral venous catheter

Central venous catheter insertion to subclavian vein

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* admission to ICU * requiring central venous catheterization * without contraindications to attempt both jugular and internal jugular access

Exclusion criteria

* the presence of a central venous catheter at admission * central venous catheterization within 2 weeks prior to admission * emergency catheterization for a life-threatening situation * major blood coagulation disorders * anatomic defect precluding catheterization at either site * skin lesions or recent surgery at either site

Design outcomes

Primary

Measure	Time frame
Time to completely insertion	1 hour

Secondary

Measure	Time frame
rates of mechanical, infectious, and thrombotic complications	14 days

Countries

Taiwan

Contacts

Primary ContactYu-Feng Wei, M.D.

ed102746@edah.org.tw+886-7-615-0011

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026