Immune Dysregulation in Hepatitis C Patients With or Without Arthritis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01195987

Enrollment

Registered

2010-09-08

Start date

2010-06-30

Completion date

2011-08-31

Last updated

2010-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis C Patients

Keywords

Hepatitis C, Arthritis

Brief summary

The purpose of this study is to study the role of the Immune System in causing arthritis in patients with Hepatitis C.

Detailed description

Patients will provide one blood sample after qualifying for the study, and signing consent. The patients will have a skin test TB, Candida, and Trichophyton placed and will read the results themselves and mail back the card with the measurements to be recorded. Labs will test for ESR, CBC, CRP, antiCCP, Cryoglobulins, RF, CH50, C3, C4, Flow cytometry, and would have already been tested for HIV and Hepatitis C.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* All adults 18 or older, 20 will have hep C positive with a viral load withen 6 mo. of enrollment. * Either interferon or antiviral naive or those who failed interferon or antiviral therapy more than 6 mo. prior to enrollment. * 10 normal healthy controls- Hep C neg and without osteoarthritis (OA).

Exclusion criteria

* HIV patients * Those with concomitant alcoholic liver disease * Patients with Rheumatoid Arthritis (RA) or other autoimmune disorders.

Countries

United States

Contacts

Primary ContactNabih I Abdou, MD, PhD

816-531-0930

Backup ContactCindy A Greenwell, RN, BSN, CCRC

cindy@centerforrheumatic.com816-531-0930

Outcome results