Fever, Malaria, Diagnosis, Referral
Conditions
Keywords
history of fever, measured fever, appropriate treatment, appropriate referral
Brief summary
Most malaria deaths occur within 48 hours of onset of symptoms, and in rural areas with poor access to health facilities, home management of malaria (HMM) can improve the timeliness of treatment and reduce malaria mortality by up to 50%. In order to maximize both coverage and impact, artemisinin combination therapies (ACTs) should be deployed in HMM programmes, as well as in formal health facilities. Up to 80% of malaria cases are treated outside the formal health sector and shops are frequently visited as the first (and in some cases only) source of treatment. Strategies to deploy ACTs in Africa thus also need to examine the role of shops in home management and to ensure that drugs sold are appropriate. The current practice of presumptive treatment of any febrile illness as malaria (both at health facilities and in the context of HMM) based solely on clinical symptoms without routine laboratory confirmation, results in significant over-use of antimalarial drugs. With ACT being a more costly regimen, it is important to be more restrictive in its administration and rapid diagnostic tests (RDTs) provide a simple means of confirming malaria diagnosis in remote locations lacking electricity and qualified health staff. This study therefore proposes to evaluate the feasibility, acceptability, and cost-effectiveness of using RDTs to improve malaria diagnosis and treatment by ocal drug shops in an area with high malaria transmission.
Interventions
Presumptive treatment of malaria/fever
Diagnosis of malaria using rapid diagnostic test
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with fever * uncomplicted malaria
Exclusion criteria
* Complicated malaria * known allergic reactions to Lumartem
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appropriateness of treatment | 36 months |
Secondary
| Measure | Time frame |
|---|---|
| Appropriateness of referral of complicated malaria cases | 36 months |
Countries
Uganda