Obstructive Sleep Apnea Syndrome
Conditions
Keywords
osteopathy
Brief summary
The main objective is to evaluate an osteopathic compression of pterygopalatine node on sleep obstructive apnea syndrome (OSA).
Detailed description
Osteopathic compression will be compared to a placebo manoeuvre. Efficacy will be assessed by measuring pharyngeal collapsibility
Interventions
PROCEDUREosteopathic compression of Pterygopalatine node
osteopathic compression of Pterygopalatine node
Sponsors
Valerie Attali
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male or Female aged 18 years or more * obstructive sleep apnea syndrome with apnea/hypopnea index \> or = 15/hour * Body mass Index \<40kg/m2
Exclusion criteria
* pregnant or lactating women * participating to another trial * acute infectious disease of upper respiratory airway tract at inclusion * facial neuralgia at inclusion * patients not able to stop treatment for OSA within one week before each visit * allergy to latex * dental extraction within 15 days before inclusion * pharyngeal surgery in the past * incapable adult
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pharyngeal critical pressure | 30 minutes after osteopathic compression | The collapsibility of the upper airway will be evaluated by pharyngeal critical pressure,assessed by measuring the intraluminal pressure associated with the cessation of airflow |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pharyngeal critical pressure | 48 hours | The collapsibility of the upper airway will be evaluated by pharyngeal critical pressure,assessed by measuring the intraluminal pressure associated with the cessation of airflow |
| symptoms | 48 hours | OSA symptoms |
| adverse events | 48 hours | clinical evaluation of adverse events |
Countries
France
Outcome results
None listed