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Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes

P06-001: (EX)Amination of (P)NH, by (L)Evel (O)f CD59 on (RE)d and White Blood Cells, in Bone Marrow Failure Syndromes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01192425
Acronym
EXPLORE
Enrollment
5580
Registered
2010-09-01
Start date
2010-09-01
Completion date
2010-09-01
Last updated
2026-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemoglobinuria

Keywords

PNH clone cells, Aplastic Anemia, AA, Myelodysplastic Syndromes, MDS, bone marrow failure syndromes, FLAER, Paroxysmal Nocturnal Hemoglobinuria

Brief summary

Examine red and white blood cells of PNH patients with bone marrow failure syndromes.

Interventions

None listed

Sponsors

Alexion Pharmaceuticals, Inc.
Lead SponsorINDUSTRY

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
10 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* At least 10 years of age. * Has aplastic anemia, myelodysplastic syndromes or other bone marrow failure syndromes

Exclusion criteria

* Has any condition that might interfere with the patient's participation

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 25, 2026