Pregnancy Outcome After In Vitro Fertilization (IVF)
Conditions
Keywords
progesterone
Brief summary
The aim is to explore whether the incidence of progesterone rise in the late follicular phase differs between GnRH-agonist and GnRH-antagonist protocols for IVF and whether this has an impact on the probability of pregnancy achievement.
Detailed description
In view of the current debate concerning possible differences in efficacy between the two GnRH analogues, the current study aimed to explore whether progesterone control in the late follicular phase differs when GnRH-agonist is used as compared to GnRH-antagonist and if so to what extend does the progesterone rise have an impact on the probability of achieving a pregnancy.
Interventions
OTHERIn vitro fertilization
In vitro fertilization procedure with gonadotropin induced follicular ovarian stimulation
Sponsors
BioGenesis
Universitair Ziekenhuis Brussel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
21 Years to 39 Years
Healthy volunteers
No
Inclusion criteria
* age \< 39 * follicle-stimulating hormone (FSH) \< 12 * gonadotropin dose 100-300IU
Exclusion criteria
* endometriosis * known endocrine disorder * blood analyzed in another laboratory
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of late progesterone rise on the day of HCG triggering | Up to delivery (2010) |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate Delivery rate | Up to delivery (2010) |
Countries
Greece
Outcome results
None listed