Hallux Valgus, Postoperative Pain
Conditions
Keywords
Day case surgery, postoperative pain, NSAIDs, Coxibs
Brief summary
The investigators hypothesize that cyclooxygenas-II-selective inhibitors (Coxibs) provide a better patients assessed overall satisfaction when used for pain management after elective hallux valgus surgery as compared to traditional Non-steroidal anti-inflammatory drugs (NSAIDs).
Detailed description
The aim of the present study is to compare patients' satisfaction with pain medication during the first 7 first postoperative days following elective hallux valgus surgery in general anaesthesia between etoricoxib and diclofenac in a prospective randomised double-blind study design.
Interventions
DRUGetoricoxib
120 mg once daily for the 1st 6 postoperative days
DRUGDiclofenac
50 mg oral 3 times daily the 1st 6 postoperative days
Sponsors
Karolinska Institutet
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiology (ASA) physiological class 1-2 patients * aged 18-65 years * scheduled for elective hallux valgus surgery in general anesthesia
Exclusion criteria
* NSAID allergy * liver disease * renal disease * uncontrolled cardiovascular disease * Lithium therapy * chronic pain * regular analgesia use
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patients Global Evaluation of Study Medication | postoperative day 1-6 | Patients self-assessment of global satisfaction with pain medication |
Outcome results
None listed